FMR LLC / FidelityAdded
- Quarter
- Mar 31, 2026
- Shares held
- 11,781,024
- Share change
- +139,696
- Value change
- +$7.05M
SEC FORM 13F
Spyre Therapeutics, Inc. Common Stock (SYRE) institutional 13F changes
Institutional holding changes reported on SEC Form 13F, classified as new, added, reduced or sold out, with a direct filing source for every row.
Last updated: 07/07/2026, 06:00 PM UTCAll SYRE stock data
- Recent 13F changes
- 12
- Institutions
- 12
- Bought / reduced
- 6 / 3
- Latest report period
- Mar 31, 2026
Institutional 13F changes
Newest filings first| Quarter | Institution | Type | Shares held | Share change | Value change | Source |
|---|---|---|---|---|---|---|
| Mar 31, 2026 | FMR LLC / Fidelity | Added | 11,781,024 | +139,696 | +$7.05M | SEC 13F ↗ |
| Mar 31, 2026 | BlackRock, Inc. | Unchanged | 5,521,221 | — | — | SEC 13F ↗ |
| Mar 31, 2026 | Perceptive Advisors LLC | Unchanged | 3,783,225 | — | — | SEC 13F ↗ |
| Mar 31, 2026 | Vanguard Capital Management LLC | New position | 3,057,401 | +3,057,401 | +$154.22M | SEC 13F ↗ |
| Mar 31, 2026 | State Street Corp | Added | 2,607,031 | +343,983 | +$17.35M | SEC 13F ↗ |
| Mar 31, 2026 | Wellington Management Group LLP | Added | 1,824,811 | +275,735 | +$13.91M | SEC 13F ↗ |
| Mar 31, 2026 | Capital International Investors | Reduced | 1,746,129 | -1,746,129 | -$88.07M | SEC 13F ↗ |
| Mar 31, 2026 | Geode Capital Management, LLC | Added | 1,720,912 | +61,402 | +$3.1M | SEC 13F ↗ |
| Mar 31, 2026 | Janus Henderson Group PLC | Unchanged | 1,656,164 | — | — | SEC 13F ↗ |
| Mar 31, 2026 | Bank of America Corp. | Added | 1,228,093 | +808,376 | +$40.77M | SEC 13F ↗ |
| Mar 31, 2026 | Franklin Resources Inc | Reduced | 882,833 | -226,254 | -$11.41M | SEC 13F ↗ |
| Mar 31, 2026 | JPMorgan Chase & Co. | Sold out | 979,299 | — | — | SEC 13F ↗ |
BlackRock, Inc.Unchanged
- Quarter
- Mar 31, 2026
- Shares held
- 5,521,221
- Share change
- —
- Value change
- —
Perceptive Advisors LLCUnchanged
- Quarter
- Mar 31, 2026
- Shares held
- 3,783,225
- Share change
- —
- Value change
- —
Vanguard Capital Management LLCNew position
- Quarter
- Mar 31, 2026
- Shares held
- 3,057,401
- Share change
- +3,057,401
- Value change
- +$154.22M
State Street CorpAdded
- Quarter
- Mar 31, 2026
- Shares held
- 2,607,031
- Share change
- +343,983
- Value change
- +$17.35M
- Quarter
- Mar 31, 2026
- Shares held
- 1,824,811
- Share change
- +275,735
- Value change
- +$13.91M
- Quarter
- Mar 31, 2026
- Shares held
- 1,746,129
- Share change
- -1,746,129
- Value change
- -$88.07M
- Quarter
- Mar 31, 2026
- Shares held
- 1,720,912
- Share change
- +61,402
- Value change
- +$3.1M
Janus Henderson Group PLCUnchanged
- Quarter
- Mar 31, 2026
- Shares held
- 1,656,164
- Share change
- —
- Value change
- —
- Quarter
- Mar 31, 2026
- Shares held
- 1,228,093
- Share change
- +808,376
- Value change
- +$40.77M
Franklin Resources IncReduced
- Quarter
- Mar 31, 2026
- Shares held
- 882,833
- Share change
- -226,254
- Value change
- -$11.41M
JPMorgan Chase & Co.Sold out
- Quarter
- Mar 31, 2026
- Shares held
- 979,299
- Share change
- —
- Value change
- —
How to read this dataset
Form 13F is filed after quarter end and can lag current holdings. Share counts may be derived from reported value and filing price; derived values are identified as calculations.