FMR LLC / FidelityAdded
- Quarter
- Jun 30, 2026
- Shares held
- 13,026,187
- Share change
- +1,245,163
- Value change
- +$562.23M
SEC FORM 13F
Spyre Therapeutics, Inc. (SYRE) institutional 13F changes
Institutional holding changes reported on SEC Form 13F, classified as new, added, reduced or sold out, with a direct filing source for every row.
Last updated: 08/13/2026, 08:05 PM UTCAll SYRE stock data
- Recent 13F changes
- 12
- Institutions
- 12
- Bought / reduced
- 9 / 1
- Latest report period
- Jun 30, 2026
Institutional 13F changes
Newest filings first| Quarter | Institution | Type | Shares held | Share change | Value change | Source |
|---|---|---|---|---|---|---|
| Jun 30, 2026 | FMR LLC / Fidelity | Added | 13,026,187 | +1,245,163 | +$562.23M | SEC 13F ↗ |
| Jun 30, 2026 | BlackRock, Inc. | Added | 6,506,605 | +985,384 | +$299.17M | SEC 13F ↗ |
| Jun 30, 2026 | Vanguard Capital Management LLC | Added | 3,448,681 | +391,280 | +$151.96M | SEC 13F ↗ |
| Jun 30, 2026 | State Street Corp | Added | 3,057,416 | +450,385 | +$139.94M | SEC 13F ↗ |
| Jun 30, 2026 | Geode Capital Management, LLC | Added | 2,562,265 | +841,353 | +$152.44M | SEC 13F ↗ |
| Jun 30, 2026 | Vanguard Portfolio Management LLC | Added | 2,330,098 | +1,744,968 | +$177.35M | SEC 13F ↗ |
| Mar 31, 2026 | Perceptive Advisors LLC | Unchanged | 3,783,225 | — | — | SEC 13F ↗ |
| Jun 30, 2026 | JPMorgan Chase & Co. | New position | 1,093,026 | +113,727 | +$54.39M | SEC 13F ↗ |
| Mar 31, 2026 | Wellington Management Group LLP | Added | 1,824,811 | +275,735 | +$13.91M | SEC 13F ↗ |
| Mar 31, 2026 | Capital International Investors | Reduced | 1,746,129 | -1,746,129 | -$88.07M | SEC 13F ↗ |
| Mar 31, 2026 | Janus Henderson Group PLC | Unchanged | 1,656,164 | — | — | SEC 13F ↗ |
| Mar 31, 2026 | Bank of America Corp. | Added | 1,228,093 | +808,376 | +$40.77M | SEC 13F ↗ |
BlackRock, Inc.Added
- Quarter
- Jun 30, 2026
- Shares held
- 6,506,605
- Share change
- +985,384
- Value change
- +$299.17M
- Quarter
- Jun 30, 2026
- Shares held
- 3,448,681
- Share change
- +391,280
- Value change
- +$151.96M
State Street CorpAdded
- Quarter
- Jun 30, 2026
- Shares held
- 3,057,416
- Share change
- +450,385
- Value change
- +$139.94M
- Quarter
- Jun 30, 2026
- Shares held
- 2,562,265
- Share change
- +841,353
- Value change
- +$152.44M
- Quarter
- Jun 30, 2026
- Shares held
- 2,330,098
- Share change
- +1,744,968
- Value change
- +$177.35M
Perceptive Advisors LLCUnchanged
- Quarter
- Mar 31, 2026
- Shares held
- 3,783,225
- Share change
- —
- Value change
- —
JPMorgan Chase & Co.New position
- Quarter
- Jun 30, 2026
- Shares held
- 1,093,026
- Share change
- +113,727
- Value change
- +$54.39M
- Quarter
- Mar 31, 2026
- Shares held
- 1,824,811
- Share change
- +275,735
- Value change
- +$13.91M
- Quarter
- Mar 31, 2026
- Shares held
- 1,746,129
- Share change
- -1,746,129
- Value change
- -$88.07M
Janus Henderson Group PLCUnchanged
- Quarter
- Mar 31, 2026
- Shares held
- 1,656,164
- Share change
- —
- Value change
- —
- Quarter
- Mar 31, 2026
- Shares held
- 1,228,093
- Share change
- +808,376
- Value change
- +$40.77M
How to read this dataset
Form 13F is filed after quarter end and can lag current holdings. Share counts may be derived from reported value and filing price; derived values are identified as calculations.